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Name |
Febuxostat |
Synonyms |
2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic Acid;UNII-101V0R1N2E;Febuxostat;Uloric;Adenuric;Tei-6720;TMX 67 |
Molecular Formula |
C16H16N2O3S |
Molecular Weight |
316.37500 |
CAS Number |
144060-53-7 |
purity |
≥99% |
Availability |
In stock |
Application: Febuxostat (INN; trade names Adenuric in Europe and New
Zealand, Uloric in the US, Goturic in Latin America, Feburic in Japan) is a
drug that inhibits xanthine oxidase, thus reducing production of uric acid in
the body. It is used in the treatment of chronic gout and hyperuricemia.
Febuxostat was discovered by scientists at the
Japanese pharmaceutical company Teijin in 1998. Teijin partnered the drug with
TAP Pharmaceuticals in the US and Ipsen in Europe. Ipsen obtained marketing
approval for febuxostat from the European Medicines Agency in April 2008,
Takeda obtained FDA approval in February 2009, and Teijin obtained approval
from the Japanese "Pharmaceuticals and Medical Devices Agency" in
2011.