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Name |
Ticagrelor |
Synonyms |
Brilinta;(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol;(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol;TICARGRELOR;Ticagrelor;AZD 6140;Brilique |
Molecular Formula |
C23H28F2N6O4S |
Molecular Weight |
522.56800 |
CAS Number |
274693-27-5 |
purity |
≥98% |
Storage conditions |
Keep in dark place,Inert atmosphere,Store in freezer,under -20°C |
Application:The clinical efficacy
and safety of ticagrelor (CAS No.: 274693-27-5), an inhibitor of platelet
aggregation, has been validated and supported by the platelet inhibition and
patient outcome study (PLATO) and multiple subgroup studies 2-11. PLATO study
also showed that ticagrelor was significantly more effective than clopidogrel,
so it was listed as the first-line recommendation by many domestic and foreign
guidelines. Moreover, in the past two years, the recommended level of
ticagrelor was listed ahead of clopidogrel in European guidelines, and
clopidogrel could only be used in patients who could not use ticagrelor.
Because ticagrelor and thienopyridine drugs (clopidogrel) are a different
chemical classification of drugs, so the former Chinese name
"ticagrelor" is replaced with "ticagrelor".