319460-85-0

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Product Description

Name	Axitinib
Synonyms	AG-013736 N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide;AXITINIB;Axtinib;AVERMECTINB;[14C]-Axitinib;Axitinib (usan)
Molecular Formula	C₂₂H₁₈N₄OS
Molecular Weight	386.47000
CAS Number	319460-85-0
purity	≥98%
Storage conditions	Sealed in dry,2-8°C

application：Axitinib (AG013736; trade name Inlyta) (CAS No.: 319460-85-0) is a small molecule tyrosine kinase inhibitor developed by Pfizer. It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models and has shown partial responses in clinical trials with renal cell carcinoma (RCC) and several other tumour types.
It was approved for RCC by the U.S. Food and Drug Administration after showing a modest increase in progression-free survival, though there have been reports of fatal adverse effects.

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