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Name |
Maitansine |
Synonyms |
maitansine;(3E,5E,7R,84S)-12c-(N-acetyl-N-methyl-L-alanyloxy)-14-chloro-10t,11c-epoxy-84-hydroxy-15,7r-dimethoxy-3,9c,11t,15-tetramethyl-(84r'H,86c'H)-15-aza-1(1,3)-benzena-8(4,6)-[1,3]oxazinana-cyclopentadecaphane-3,5-diene-82,14-dione |
Molecular Formula |
C34H46ClN3O10 |
Molecular Weight |
692.19600 |
CAS Number |
35846-53-8 |
purity |
≥98% |
Storage conditions |
Sealed in dry,Room Temperature |
application:Maitansine
(INN), or maytansine (USAN) (CAS No.: 35846-53-8), is a cytotoxic agent. It inhibits the assembly of
microtubules by binding to tubulin at the rhizoxin binding site.
It is a macrolide of the ansamycin type and can
be isolated from plants of the genus Maytenus.
Derivatives are known as maytansinoids.