607742-69-8

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Product Description

Name	SB-742457
Synonyms	3-(benzenesulfonyl)-8-piperazin-1-ylquinoline；Quinoline,3-(phenylsulfonyl)-8-(1-piperazinyl)
Molecular Formula	C₁₉H₁₉N₃O₂S
Molecular Weight	353.43800
CAS Number	607742-69-8
purity	≥98%
Storage conditions	Keep in dark place,Inert atmosphere,2-8°C

Applications：

Intepirdine (INN; developmental codes SB-742457, RVT-101) (CAS:607742-69-8) is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects. It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease and demonstrated some preliminary efficacy in phase II clinical trials; however, GSK chose not to continue development and sold the rights to Axovant Sciences in December 2014.

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