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Name |
Empagliflozin |
Synonyms |
X5927;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;Empagliflozin;CS-0940 |
Molecular Formula |
C23H27ClO7 |
Molecular Weight |
450.90900 |
CAS Number |
864070-44-0 |
purity |
≥99% |
Storage conditions |
Sealed in dry,2-8°C |
Availability |
In stock |
Application: Empagliflozin (CAS No.: 864070-44-0) is a new generation SGLT2 inhibitor (type 2 sodium-glucose transporter
inhibitor) approved by the U.S. Food and Drug Administration (FDA) in August
2014 for the treatment of adults with type 2 diabetes mellitus in combination
with diet and exercise. Englistin reduces the ability of the kidneys to recycle
glucose back into the bloodstream and allows sugar to be excreted through the
urine, significantly reducing patients' blood glucose levels, risk of kidney
and cardiovascular disease, overweight and blood pressure. Different from other
oral drugs currently used in the treatment of type 2 diabetes, englisin is the
first SGLT2 class hypoglycemic agent to complete the cardiovascular prognosis
study, and it is the only oral hypoglycemic agent to be proved to have the
efficacy of controlling glucose, protecting heart, protecting kidney and
reducing body weight.