86541-75-5
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86541-75-5

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Product Description

Name

Benazepril

Synonyms

Benazeprilum;Benazepril [INN:BAN];2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid;Benazeprilum [Latin];(3S)-1-(carboxymethyl)-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one;benzazepril

Molecular Formula

C24H28N2O5

Molecular Weight

424.49000

CAS Number

86541-75-5

purity

98%

Storage conditions

Sealed in dry,2-8°C











Application:Benazepril (CAS No.: 86541-75-5), brand name Lotensin (Novartis), is an ACE inhibitor used primarily in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing the renal and retinal complications of diabetes.
ACE inhibitors relax blood vessels, and decrease blood volume, which lowers blood pressure and decreases oxygen demand from the heart. They inhibit angiotensin-converting enzyme, which is part of the renin–angiotensinaldosterone system.
Benazepril is a prodrug which is metabolized by the liver into its active form benazeprilat via cleavage of the drug's ester group.


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